Mayo Model Knowledge

• The Mayo Model is a clinical prediction model developed by the Mayo Clinic to assess the malignancy risk of lung nodules.
• The model is based on six variables: age, smoking history, cancer history, nodule diameter, nodule location, and nodule type.
• The model is applicable to incidentally found lung nodules and not to patients with known lung cancer or obvious symptoms.
• Risk assessment results can help doctors and patients decide whether further examination or follow-up is needed.
• Low-risk nodules can usually be followed up regularly, while high-risk nodules may require biopsy or surgical resection.
• Mayo Model formula: p = e^x / (1 + e^x), where x = -6.8272 + 0.0391×age + 0.7917×smoking history + 1.3388×cancer history + 0.1274×nodule diameter + 0.7838×upper lobe + 1.0407×spiculation. (Smoking history, cancer history, upper lobe, spiculation: Yes=1, No=0)